25 Powerful Prayers for Protection and Safety From Harm and Enemies

Here are the 25 most powerful prayers for protection and safety from harm and enemies.

Shield of Faith Prayer
Father, I come to You today, bowing in my heart, asking for protection from the evil one. Lord, we are assailed moment by moment with images on television, the internet, books, and newspapers that leave us vulnerable to sin of every kind. Surround us with Your divine hedge of protection. Encompass us round about with Your strength and Your might. Let all who take refuge in You be glad, let them ever sing for joy. And may You shelter us, that those who love Your name may exult in You. For it is You who blesses the righteous man, O LORD, You surround him with your shield of faith. Through Jesus Christ our Lord, Amen.

Power of Spirit Prayer
Lord, I ask that You protect our minds. Father, the mindset on the flesh is death, but the mindset on the Spirit is life and peace. O God set our minds on You. Let us not be conformed to this world, but be transformed by the renewing of our minds that we may prove what Your will is, that which is good and acceptable and perfect. Help us by the power of Your Spirit to think on whatever is true, whatever is honorable, whatever is right, whatever is pure, whatever is lovely, and whatever is of good repute. If there is any excellence and if anything is worthy of praise, let our minds dwell on these things. Through Jesus Christ our Lord, Amen.

Dress Us in Armor Prayer
Strengthen us in the power of Your might, O God. Dress us in Your armor so that we can stand firm against the schemes of the devil. We know that our struggle is not against flesh and blood, but against the rulers, against the powers, against the world forces of this darkness, and against the spiritual forces of wickedness in the heavenly places. Through Jesus Christ our Lord, Amen.

Guard Me Prayer
Lord, I pray for Your emotional, physical, and spiritual protection over me. Keep evil far from me, and help me to trust You as my refuge and strength. I pray You will guard my mind from harmful instruction, and grant me discernment to recognize truth. Through Jesus Christ our Lord, Amen.

Spiritual Shelter Prayer
My God and My Lord, I pray You will make me strong and courageous in the presence of danger, recognizing that You have overcome and will set right all injustice and wrong one day. Help me to find rest in Your shadow, as I live in the spiritual shelter You provide for me. Let me know that the only safe place is in Jesus and that my home on earth is only temporary. Through Jesus Christ our Lord, Amen.

One Who fights Prayer
Lord God, I pray for Your protection as I begin this day. You are my hiding place, and under Your wings I can always find refuge. Protect me from trouble wherever I go, and keep evil far from me. No matter where I am, I will look to You as my Protector, the One Who fights for me every day. Through Jesus Christ our Lord, Amen.

Surround Me Prayer
My God, I ask that Your spirit may keep all evil away and all love nearby. Your love and faithfulness, along with Your goodness and mercy, surround me daily, so I will not fear whatever might come against me. My trust is in You, God, and I give thanks to You for Your love and protection. Through Jesus Christ our Lord, Amen.

Hold Him Prayer
Lord Jesus, I ask You to protect (insert name of person) and shield him from danger. Make him strong, defined by Your character, so that he can lean hard on You for wisdom in any situation. Guard him by the power of Your name, and allow nothing formed against him to prosper. Hold him close to Your heart, with his eyes focused always on You. At home, work, or wherever he goes, keep his heart and thoughts pure. Through Jesus Christ our Lord, Amen.

I am Weak Prayer
Lord, I am weak to the temptations and dangers of life. Lead me away from temptation, and help me to be continually aware of my enemy’s efforts to distract, deceive, or discourage me. Cancel every attempt to discredit my name or my salvation. May Your right hand strengthen me daily as You guard me with your presence. Through Jesus Christ our Lord, Amen.

Faith-Rooted Prayer
My God, watch over (insert name here). Help him wear his spiritual armor well, as he tries to lead his family with integrity and honor. Seal up the exits that cry for escape when responsibilities grow heavy on his shoulders. Thank You that You promise to carry his burdens and lighten his load in the daily battles of life. Preserve his testimony and keep his faith rooted deeply in You, Lord. You are his sure defense, and You are the only One who can truly keep him safe. Through Jesus Christ our Lord, Amen.

Your Loving Care Prayer
Father, I entrust myself into Your loving care. You are the most powerful influence in my life, so I ask You to surround me with Your constant presence and safety. Because You love your children, You are even more concerned than I am with myself. You take our protection seriously. Place Your Holy Spirit around me like a bubble that deflects any harm aimed my way. Through Jesus Christ our Lord, Amen.

Guard my Loved Ones Prayer
My Lord, please guard my loved ones from the dangers of the world, whether from outside or inside. Place Your angels in strategic places, ready to move on their behalf. Let no evil come near them. Give them a steadfast faith and trust in You that puts their fears at rest, knowing they will live in safety with Your solid protection. Through Jesus Christ our Lord, Amen.

Guard my Friends Prayer
My God, Guard my friends from temptation and those who would try to make them compromise their convictions. When trouble comes, let them cry out to You. May their security rest not in this world, but in their relationship with You and in their eternal future. Impress on them daily that this world is not their final home, and that nothing and no one can ever separate them from Your love. Through Jesus Christ our Lord, Amen.

Angels Hover Prayer
Lord Jesus, evil is such a harsh word, and yet Your Word uses it frequently to describe the opposite of good. While we are all capable of sin, I ask Your protection against those who call good evil, and evil good. Guard us against those who scheme against righteousness and from those who twist truth into lies to accomplish their evil intents. May Your angels hover ever near to eradicate fear and fight against dark, spiritual forces we cannot see. Through Jesus Christ our Lord, Amen.

Fateful Blow Prayer
My Lord and My God, Help us cast down every imagination and thought that our enemy tries to use to exalt itself against You. You dealt our spiritual enemy a fateful blow on Calvary when you died on the cross for us and were resurrected on the third day. While evil still roams, the power of Your name and Your blood rises up to defeat and bring us victory against every evil planned against us. Through Jesus Christ our Lord, Amen.

Bring Justice Prayer
Oh God, protect us. While malicious actions may disturb us, we use the armor of God You have given us to stand firm. You will bring justice in due time for all the harm and needless violence aimed at Your children. Until then, we remain in Your presence, aligned with Your purposes, and we look to You as our Supreme Commander and Protector. Help us to avoid temptation, and deliver us from evil, Lord. Through Jesus Christ our Lord, Amen.

Protect Our Family Prayer
Precious Jesus, You know what it means to be pursued by earthly enemies. And because of Your compassion and understanding, You know the harm our families face every day. As Christians and followers of Yours, we will be marked as enemies. Our children need protection from bullies, from misguided avengers, and from false philosophies that attack their spiritual heritage. But as long as you are here, we fear no enemies. Through Jesus Christ our Lord, Amen.

Victory Prayer
Oh God, please command Your angels to keep us in all our ways, so that no harm or disaster will come near to our home or our lives. Our trust is not in our ability but in Your stability. Our weapons of warfare are spiritual, and we look to You for victory. Show us when to speak up, when to listen, and when to act… always aware that You are fighting our battles for us and with us. Teach us to love our enemies, to pray for them, but to resist evil in Your powerful name. Through Jesus Christ our Lord, Amen.

Righteous Reverence Prayer
My Lord, we have enemies but we also have You by our side. We don’t fear those who might try to hurt us physically. We are confident in our eternal security. Our fear is a holy, righteous reverence based on Who You are and Whose we have become in You. As Commander and Chief, You will defend us from all earthly enemies. Through Jesus Christ our Lord, Amen.

Watch Before us Prayer
Lord God, I pray for Your protection everywhere. Our influence, our priorities, and our character are tested daily. Help us to remember that every foolish action reaps consequences, and every careless word carries weight among our brothers. Others are watching, Lord, so set a watch before our mouths and guard the door of our lips. Through Jesus Christ our Lord, Amen.

Protective Love Prayer
Lord, please keep us from those who seek to speak ill of us. Protect us from those who try to sway our convictions or tempt us to compromise our standards in the name of success. Place an invisible banner over us that reminds us of Your protective love and that we belong to You. Our reputation is important to You, so turn us away from misplaced priorities. When others aim criticism our way or when misunderstanding arises, guard us from impatience or anger. Through Jesus Christ our Lord, Amen.

High Road of Love Prayer
My God, protect us from our own sinful nature and help us to always take the high road of love. Thank You for Your promise never to leave us or abandon us, and that Your Spirit lives inside of us to give wisdom, understanding, and security against those who want to pull us away or harm us. You are Lord and we look to You to preserve all graces that come from you. Through Jesus Christ our Lord, Amen.

Healer Prayer
We bless You, Lord, for You are our Jehovah Rapha, the Healer of all our diseases. Our body is the temple of Your Spirit, so we pray for protection from that which could bring harm to us physically. Guard us from stresses that steal our emotional strength and lower our immunity to fight infection. Heal us of past traumas that may affect our present or future health. Through Jesus Christ our Lord, Amen.

Great Physician Prayer
My God, we fear harm from illness. Teach us how to discipline our bodies so we can grow stronger and increase our physical stamina. When challenges arise, we need not fear, for You have given us a spirit of power, of love, and a sound mind. As the Great Physician, You know us so well. You ordained every part of our body even before we were born. Help us to treat our bodies with respect as Your beloved creations. Through Jesus Christ our Lord, Amen.

Safeguard Us Prayer
My Lord, my God, We want to serve You with excellence, so in our weakness, grant us strength and good health so that nothing will prevent Your plan for our lives. Protect us from contagions and diseases that can riddle the body and bring dangerous results. Safeguard us with wisdom to use the rest You provide as we wait on You and with You daily. Our lives and our health are in Your hands, Lord, and our trust and faith are in You. Through Jesus Christ our Lord, Amen.

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Read More of the Most Powerful Prayers

25 Powerful Prayers for Healing, Recovery and Strength
25 Powerful Prayers for Forgiveness of Sins and Others
25 Powerful Prayers for Faith and Guidance
25 Powerful Prayers for Peace of Mind, Comfort and Understanding


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